Research

At the University of Florida, we’re asking questions to advance knowledge and understanding of diabetes through the collaboration of patient care providers, researchers and education leaders from multiple disciples under one roof. Our people are conducting basic research to clarify the mechanisms causing diabetes and related complications, and translational research to transform their research findings into clinical solutions. The shared technologies made available through resources provided by the University of Florida and private philanthropy allow our investigators to continue conducting state-of-the-art clinical research trials, moving us closer to a cure for diabetes.

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Kenneth Cusi, M.D.

Dulaglutide decreases plasma aminotransferases in people with Type 2 diabetes in a pattern consistent with liver fat reduction

Jun 15th, 2018

This study evaluated the effects of dulaglutide vs placebo on liver and glycaemic/metabolic measurements in a population with Type 2 diabetes and in a subgroup with non-alcoholic fatty liver/non-alcoholic steatohepatitis.Once-weekly […]

Colorful Syringes

Immature Dendritic Cell Therapy Confers Durable Immune Modulation in an Antigen-Dependent and Antigen-Independent Manner in Nonobese Diabetic Mice.

May 8th, 2018

Dendritic cell (DC) immunotherapy has been effective for prevention of type 1 diabetes (T1D) in NOD mice but fails to protect if initiated after active autoimmunity. As autoreactivity expands inter- and […]

Body Scan

Informational value of percent body fat with body mass index for the risk of abnormal blood glucose: a nationally representative cross-sectional study.

May 7th, 2018

To examine the value of percent body fat (%BF) with body mass index (BMI) to assess the risk of abnormal blood glucose (ABG) among US adults who are normal weight […]

Cytokeratin-18 and enhanced liver fibrosis scores in type 1 and type 2 diabetes and effects of two different insulins

Cytokeratin-18 and enhanced liver fibrosis scores in type 1 and type 2 diabetes and effects of two different insulins

Mar 2nd, 2018

Data on cytokeratin-18 (K-18) and enhanced liver fibrosis (ELF) score in insulin-treated diabetes patients with non-alcoholic fatty liver disease (NAFLD) are limited. This study analyzed phase III data comparing basal insulin […]

liver

Clinical and Histologic Characterization of Nonalcoholic Steatohepatitis in African American Patients

Mar 2nd, 2018

  There has been a widespread misconception among physicians that African Americans are protected from developing nonalcoholic steatohepatitis (NASH). However, a formal histologic and metabolic comparison against well-matched Caucasians has […]