Research

At the University of Florida, we’re asking questions to advance knowledge and understanding of diabetes through the collaboration of patient care providers, researchers and education leaders from multiple disciples under one roof. Our people are conducting basic research to clarify the mechanisms causing diabetes and related complications, and translational research to transform their research findings into clinical solutions. The shared technologies made available through resources provided by the University of Florida and private philanthropy allow our investigators to continue conducting state-of-the-art clinical research trials, moving us closer to a cure for diabetes.

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Cytokeratin-18 and enhanced liver fibrosis scores in type 1 and type 2 diabetes and effects of two different insulins

Cytokeratin-18 and enhanced liver fibrosis scores in type 1 and type 2 diabetes and effects of two different insulins

Mar 2nd, 2018

Data on cytokeratin-18 (K-18) and enhanced liver fibrosis (ELF) score in insulin-treated diabetes patients with non-alcoholic fatty liver disease (NAFLD) are limited. This study analyzed phase III data comparing basal insulin […]

liver

Clinical and Histologic Characterization of Nonalcoholic Steatohepatitis in African American Patients

Mar 2nd, 2018

  There has been a widespread misconception among physicians that African Americans are protected from developing nonalcoholic steatohepatitis (NASH). However, a formal histologic and metabolic comparison against well-matched Caucasians has […]

T Cells

New-onset diabetes after kidney transplantation: can the risk be modified by choosing immunosuppression regimen based on pretransplant viral serology?

Mar 2nd, 2018

This study aimed to analyze adult kidney transplant recipients (KTRs) for the risk of new-onset diabetes after transplantation (NODAT) associated with viral serologies and immunosuppression regimens [tacrolimus (Tac) + mycophenolate (MPA), […]

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets (Journal of Proteome Research)

Jun 8th, 2017

The transplantation of human pancreatic islets is a therapeutic possibility for a subset of type 1 diabetic patients who experience severe hypoglycemia. Pre- and post-transplantation loss in islet viability and […]

Liver Safety of Statins in Prediabetes or T2DM and Nonalcoholic Steatohepatitis: Post-hoc Analysis of a Randomized Trial (Journal of Clinical and Endocrinology Metabolism)

Jun 8th, 2017

The purpose of this study was to perform a prospective assessment of the long-term safety of statins in patients with prediabetes/T2DM and NASH. The authors concluded that statin therapy is […]