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Dulaglutide decreases plasma aminotransferases in people with Type 2 diabetes in a pattern consistent with liver fat reduction

This study evaluated the effects of dulaglutide vs placebo on liver and glycaemic/metabolic measurements in a population with Type 2 diabetes and in a subgroup with non-alcoholic fatty liver/non-alcoholic steatohepatitis.Once-weekly dulaglutide improved alanine aminotransferase, aspartate transaminase and gamma-glutamyl transpeptidase levels compared with placebo in a pattern consistent with…

Dr. Matthew Gurka to Serve on NIH Study Section

Matthew Gurka, Ph.D., a professor in the Department of Health Outcomes and Biomedical Informatics (HOBI) at UF and associate director of UF’s Institute for Child Health Policy (ICHP), was selected to serve as a member of the National Institutes of Health’s (NIH’s) Kidney, Nutrition, Obesity…

Immature Dendritic Cell Therapy Confers Durable Immune Modulation in an Antigen-Dependent and Antigen-Independent Manner in Nonobese Diabetic Mice.

Dendritic cell (DC) immunotherapy has been effective for prevention of type 1 diabetes (T1D) in NOD mice but fails to protect if initiated after active autoimmunity. As autoreactivity expands inter- and intramolecularly during disease progression, we investigated whether DCs unpulsed or pulsed with β cell antigenic dominant determinants (DD), subdominant determinants…

Informational value of percent body fat with body mass index for the risk of abnormal blood glucose: a nationally representative cross-sectional study.

To examine the value of percent body fat (%BF) with body mass index (BMI) to assess the risk of abnormal blood glucose (ABG) among US adults who are normal weight or overweight. We hypothesised that normal-weight population with higher %BF is more likely to have ABG.   Read More: http://bmjopen.bmj.com/content/8/4/e019200.long …