T32 Mentors

Stem cell differentiation and biomaterials for diabetes therapies

Identifying markers of endothelial-vascular biology and immunology to understand T1D progression

Understanding T1D pathogenesis and a means to prevent/cure the disease

Developing relevant statistical methods and computational software addressing important challenges in genomics, epigenomics, and biomedical research

Evaluating combination immunotherapies for type 1 diabetes using animal and in vitro models

Spatial biology of human tissues during pediatric development and in T1D

Utilizing cutting edge technologies, AI and genetics to understand T1D pathogenesis and response to therapies

Centering the psychology of T1D patients and families to understand & predict their usage of novel management and treatment tools

Adapting clinical Natural Language Processing to provide early detection of diabetic retinopathy

Immunotherapy trials for the prevention and reversal of T1D

Incorporating nanomaterials in the design of T1D immunotherapies

Translating findings from large-scale longitudinal T1D studies into pediatric care 

Designing dendritic cell behavior modifiers using antigen-loaded nanoparticles to prevent and reverse T1D

Manipulating gut bacteria to prime diabetogenic T cells

Development of biomaterial systems that can manipulate the immune system

Investigating pancreatic islet microenvironments in human donor tissue 

Measuring metabolic flux with isotope tracers and performing NMR and GC-MS metabolomics to assess metabolic homeostasis

Development of antibody responses in autoimmune disease and transplantation

Polymer Synthesis, Hydrogels, Drug Delivery, Bioprinting, Tissue Engineering and Regenerative Medicine

Investigating the role of pancreatic islets in beta cell dysfunction & autoimmunity in T1D

Studying how brain pathologies affect the neurovascular unit and how these changes lead to the disruption of the Blood-Brain Barrier (BBB).

Cellular engineering and regenerative medicine approaches to restore beta cell function in human type 1 diabetes (T1D)

Examining the American Indian experience of diabetes, including T1D

Addressing islet transplantation complications with novel immunomodulatory biomaterials 

Applying pancreatic characteristics to T1D histopathology and identifying biomarkers of disease

Clinical and Health Psychology and behavioral medicine approaches for addressing biopsychosocial aspects of type 1 diabetes