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Kenneth Cusi, M.D.

Dulaglutide decreases plasma aminotransferases in people with Type 2 diabetes in a pattern consistent with liver fat reduction

Published: Jun 15th, 2018

This study evaluated the effects of dulaglutide vs placebo on liver and glycaemic/metabolic measurements in a population with Type 2 diabetes and in a subgroup with non-alcoholic fatty liver/non-alcoholic steatohepatitis.Once-weekly […]

Colorful Syringes

Immature Dendritic Cell Therapy Confers Durable Immune Modulation in an Antigen-Dependent and Antigen-Independent Manner in Nonobese Diabetic Mice.

Published: May 8th, 2018

Dendritic cell (DC) immunotherapy has been effective for prevention of type 1 diabetes (T1D) in NOD mice but fails to protect if initiated after active autoimmunity. As autoreactivity expands inter- and […]

Body Scan

Informational value of percent body fat with body mass index for the risk of abnormal blood glucose: a nationally representative cross-sectional study.

Published: May 7th, 2018

To examine the value of percent body fat (%BF) with body mass index (BMI) to assess the risk of abnormal blood glucose (ABG) among US adults who are normal weight […]

Cytokeratin-18 and enhanced liver fibrosis scores in type 1 and type 2 diabetes and effects of two different insulins

Cytokeratin-18 and enhanced liver fibrosis scores in type 1 and type 2 diabetes and effects of two different insulins

Published: Mar 2nd, 2018

Data on cytokeratin-18 (K-18) and enhanced liver fibrosis (ELF) score in insulin-treated diabetes patients with non-alcoholic fatty liver disease (NAFLD) are limited. This study analyzed phase III data comparing basal insulin […]

liver

Clinical and Histologic Characterization of Nonalcoholic Steatohepatitis in African American Patients

Published: Mar 2nd, 2018

  There has been a widespread misconception among physicians that African Americans are protected from developing nonalcoholic steatohepatitis (NASH). However, a formal histologic and metabolic comparison against well-matched Caucasians has […]

T Cells

New-onset diabetes after kidney transplantation: can the risk be modified by choosing immunosuppression regimen based on pretransplant viral serology?

Published: Mar 2nd, 2018

This study aimed to analyze adult kidney transplant recipients (KTRs) for the risk of new-onset diabetes after transplantation (NODAT) associated with viral serologies and immunosuppression regimens [tacrolimus (Tac) + mycophenolate (MPA), […]

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets (Journal of Proteome Research)

Published: Jun 8th, 2017

The transplantation of human pancreatic islets is a therapeutic possibility for a subset of type 1 diabetic patients who experience severe hypoglycemia. Pre- and post-transplantation loss in islet viability and […]

Liver Safety of Statins in Prediabetes or T2DM and Nonalcoholic Steatohepatitis: Post-hoc Analysis of a Randomized Trial (Journal of Clinical and Endocrinology Metabolism)

Published: Jun 8th, 2017

The purpose of this study was to perform a prospective assessment of the long-term safety of statins in patients with prediabetes/T2DM and NASH. The authors concluded that statin therapy is […]

Mary Tyler Moore (1936-2017): Diabetes Educator and Advocate (Diabetes Care)

Published: May 25th, 2017

Dr. Atkinson and Dr. Nierras wrote a beautiful piece on how Mary Tyler Moore’s courage and strength in the face of her diabetes diagnosis has inspired and lent courage to […]

Comparitive Pathogenesis of Autoimmune Diabetes in humans, NOD Mice, and Canines: Has a Valuable Animal Model of Type 1 Diabetes Been Overlooked? (Diabetes)

Published: May 25th, 2017

Despite decades of research in humans and mouse models of disease, substantial gaps remain in our understanding of pathogenic mechanisms underlying the development of type 1 diabetes. Furthermore, translation of therapies […]