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Immature Dendritic Cell Therapy Confers Durable Immune Modulation in an Antigen-Dependent and Antigen-Independent Manner in Nonobese Diabetic Mice.

Published: May 8th, 2018

Dendritic cell (DC) immunotherapy has been effective for prevention of type 1 diabetes (T1D) in NOD mice but fails to protect if initiated after active autoimmunity. As autoreactivity expands inter- and […]

Body Scan

Informational value of percent body fat with body mass index for the risk of abnormal blood glucose: a nationally representative cross-sectional study.

Published: May 7th, 2018

To examine the value of percent body fat (%BF) with body mass index (BMI) to assess the risk of abnormal blood glucose (ABG) among US adults who are normal weight […]

Cytokeratin-18 and enhanced liver fibrosis scores in type 1 and type 2 diabetes and effects of two different insulins

Cytokeratin-18 and enhanced liver fibrosis scores in type 1 and type 2 diabetes and effects of two different insulins

Published: Mar 2nd, 2018

Data on cytokeratin-18 (K-18) and enhanced liver fibrosis (ELF) score in insulin-treated diabetes patients with non-alcoholic fatty liver disease (NAFLD) are limited. This study analyzed phase III data comparing basal insulin […]

liver

Clinical and Histologic Characterization of Nonalcoholic Steatohepatitis in African American Patients

Published: Mar 2nd, 2018

  There has been a widespread misconception among physicians that African Americans are protected from developing nonalcoholic steatohepatitis (NASH). However, a formal histologic and metabolic comparison against well-matched Caucasians has […]

T Cells

New-onset diabetes after kidney transplantation: can the risk be modified by choosing immunosuppression regimen based on pretransplant viral serology?

Published: Mar 2nd, 2018

This study aimed to analyze adult kidney transplant recipients (KTRs) for the risk of new-onset diabetes after transplantation (NODAT) associated with viral serologies and immunosuppression regimens [tacrolimus (Tac) + mycophenolate (MPA), […]

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets (Journal of Proteome Research)

Published: Jun 8th, 2017

The transplantation of human pancreatic islets is a therapeutic possibility for a subset of type 1 diabetic patients who experience severe hypoglycemia. Pre- and post-transplantation loss in islet viability and […]

Liver Safety of Statins in Prediabetes or T2DM and Nonalcoholic Steatohepatitis: Post-hoc Analysis of a Randomized Trial (Journal of Clinical and Endocrinology Metabolism)

Published: Jun 8th, 2017

The purpose of this study was to perform a prospective assessment of the long-term safety of statins in patients with prediabetes/T2DM and NASH. The authors concluded that statin therapy is […]

Mary Tyler Moore (1936-2017): Diabetes Educator and Advocate (Diabetes Care)

Published: May 25th, 2017

Dr. Atkinson and Dr. Nierras wrote a beautiful piece on how Mary Tyler Moore’s courage and strength in the face of her diabetes diagnosis has inspired and lent courage to […]

Comparitive Pathogenesis of Autoimmune Diabetes in humans, NOD Mice, and Canines: Has a Valuable Animal Model of Type 1 Diabetes Been Overlooked? (Diabetes)

Published: May 25th, 2017

Despite decades of research in humans and mouse models of disease, substantial gaps remain in our understanding of pathogenic mechanisms underlying the development of type 1 diabetes. Furthermore, translation of therapies […]

Analgesic Antipyretic Use Among Young Children in the TEDDY Study: No Association With Islet Autoimmunity (BMC Pediatric)

Published: May 25th, 2017

The aim of this study was to analyze patterns of analgesic antipyretic use across the clinical centers of The Environmental Determinants of Diabetes in the Young (TEDDY) prospective cohort study and test […]