UFDI Investigator Desmond Schatz, M.D. and other researchers found that vitamin D insufficiency is present in a substantial proportion of youth with diabetes, particularly minorities, but the prevalence appears similar to that in youth without diabetes.
UFDI Investigator Michael Haller, M.D. and other researchers found that among overweight adolescents with type 1 diabetes, the addition of metformin to insulin did not improve glycemic control after 6 months.
UFDI and nPOD investigators found that the presence of β-cells as well as insulitis several years after T1D diagnosis in children and young adults suggest that the chronicity of islet autoimmunity extends well into the post-diagnosis period.
UFDI researchers Amanda Posgai, Ph.D. and Mark Atkinson, Ph.D. and collaborators examine a new approach for preserving beta cell function in patients with recent onset T1D.
UF Researchers Shannon Wallet, Ph.D. and Christina Graves, along with collaborators, studied human noroviruses, which are a leading cause of foodborne disease and severe childhood diarrhea, as well as a cause of gastroenteritis outbreaks worldwide.
UFDI Researcher Patrick Concannon, Ph.D. and collaborators found evidence that suggests that a small set of regulatory elements specify the regulatory T cell (Treg) lineage and that genetic variation in Treg cell-specific enhancers may alter Treg cell function contributing to polygenic disease.
UFDI researcher Anastasia Albanese-O’Neill, Ph.D., ARNP, CDE contributed to this ADA publication in Diabetes Care.
They found that clinically significant anxiety among children who are overweight or obese is associated with increased body dissatisfaction and parent psychological distress, as well as decreased health-related quality of life.
UFDI investigators and collaborators found that granulocyte colony stimulating factor monotherapy did not affect C-peptide production, HbA1c, or insulin dose.This study supports the continued exploration of G-CSF and other mobilizing agents in subjects with T1D, but only when combined with immunodepleting agents where synergistic mechanisms of action have previously demonstrated…
UFDI Investigator Janet Silverstein, M.D. and collaborators examined the frequency of depressive symptoms among youth with T1D and T2D enrolled in Pediatric Diabetes Consortium registries. They identified depression symptoms in 13 percent of T1D and 22 percent of T2D participants. For youths with T1D, but not T2D, depressive symptoms correlated…