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Islet cell hyperexpression of HLA class 1 antigens: a defining feature in type 1 diabetes (Diabetologia)

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The researchers explored whether HLA class 1 hyperexpression could be a valid explanation for the demise of pancreatic beta cells in type 1 diabetes.

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Richardson SJ, Rodriguez-Calvo T, Gerling IC, Mathews CE, Kaddis JS, Russell MA, Zeissler M, Leete P, Krogvold L, Dahl-Jørgensen K, von Herrath M, Pugliese A, Atkinson MA, Morgan NG. (2016). Islet cell hyperexpression of HLA class 1 antigens: a defining feature in type 1 diabetes. Diabetologia. 2016 Aug 9.