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Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes

Published: Nov 21st, 2015

UFDI and nPOD investigators found that the presence of β-cells as well as insulitis several years after T1D diagnosis in children and young adults suggest that the chronicity of islet […]


Immune Depletion in Combination with Allogeneic Islets Permanently Restores Tolerance to Self-Antigens in Diabetic NOD Mice

Published: Nov 20th, 2015

UFDI researchers Amanda Posgai, Ph.D. and Mark Atkinson, Ph.D. and collaborators examine a new approach for preserving beta cell function in patients with recent onset T1D.

Shannon Wallet

Human norovirus culture in B cells

Published: Oct 30th, 2015

UF Researchers Shannon Wallet, Ph.D. and Christina Graves, along with collaborators, studied human noroviruses, which are a leading cause of foodborne disease and severe childhood diarrhea, as well as a […]

Pat Concannon (2)

Genetic and epigenetic variation in the lineage specification of regulatory T cells

Published: Oct 29th, 2015

UFDI Researcher Patrick Concannon, Ph.D. and collaborators found evidence that suggests that a small set of regulatory elements specify the regulatory T cell (Treg) lineage and that genetic variation in […]


Diabetes Care in the School Setting: A Position Statement of the American Diabetes Association

Published: Oct 21st, 2015

UFDI researcher Anastasia Albanese-O’Neill, Ph.D., ARNP, CDE contributed to this ADA publication in Diabetes Care.


UF investigators analyze associations between anxiety symptoms and family factors in pediatric obesity

Published: Oct 20th, 2015

They found that clinically significant anxiety among children who are overweight or obese is associated with increased body dissatisfaction and parent psychological distress, as well as decreased health-related quality of […]


Mobilization without immune depletion fails to restore immunological tolerance or preserve beta cell function in recent onset type 1 diabetes

Published: Oct 18th, 2015

UFDI investigators and collaborators found that granulocyte colony stimulating factor monotherapy did not affect C-peptide production, HbA1c, or insulin dose.This study supports the continued exploration of G-CSF and other mobilizing […]

Silverstein, Janet_5836_Kiewel

Depressive symptoms in type 1 and type 2 diagnosed youth

Published: Oct 18th, 2015

UFDI Investigator Janet Silverstein, M.D. and collaborators examined the frequency of depressive symptoms among youth with T1D and T2D enrolled in Pediatric Diabetes Consortium registries. They identified depression symptoms in […]


Immunoproteomic Profiling of Anti-Viral Antibodies in New-Onset Type 1 Diabetes Using Protein Arrays

Published: Oct 12th, 2015

UFDI investigators and collaborators at Arizona State University found that the Epstein-Barr virus may have a role in type 1 diabetes development.

UFDI Investigator Patrick Concannon, Ph.D.

Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes

Published: Oct 10th, 2015

UFDI researcher Patrick Concannon, Ph.D. and other collaborators found that four loci were associated with autoantibody positivity at genome-wide significance in type 1 diabetes.